Title

Additional reduction in blood pressure after cholesterol-lowering treatment with statins (lovastatin or pravastatin) in hypercholesterolemic patients using angiotensin-converting enzyme inhibitors (enalapril or lisinopril).

Purpose

To evaluate the effect on blood pressure after cholesterol-lowering treatment with statins (lovastatin or pravastatin) in hypercholesterolemic patients using angiotensin-converting enzyme inhibitors (enalapril or lisinopril)

Patients

Hypercholesterolemic patients using ACE inhibitors
Additional reduction in blood pressure after cholesterol-lowering
treatment with statins (lovastatin or pravastatin) in
hypercholesterolemic patients using angiotensin-converting
enzyme inhibitors (enalapril or lisinopril)

Follow-up

16 weeks

Treatment regimen

ACE inhibitors alone vs. ACE inhibitors + statins

Results

Statin-treated group had a greater reduction in BP and total cholesterol levels at week 16

Conclusion

The study suggests a synergistic effect between cholesterol lowering with statins and ACE inhibitors for hypertensive patients.