Acyclovir
Indications
Acivir is indicated for the treatment of Herpes
simplex virus infections of the skin and mucous membrane,
including initial and recurrent genital herpes, suppression
of recurrent Herpes simplex infections in immunocompetent
patients; prophylaxis of Herpes simplex infection in immunocompromised
patients; varicella (chicken pox) and Herpes zoster (shingles)
infections; and management of severely immunocompromised,
namely those with HIV disease (CD4+ counts
< 200/mm3, including patients with AIDS or severe ARC)
or after bone marrow transplantation.
Dosage and Administration
TREATMENT OF GENITAL HERPES
Initial
200 mg every four hours, five times daily for 10 days.
Chronic suppressive therapy
400 mg twice daily for up to 12 months.
Intermittent therapy
200 mg five times daily for five days.
Treatment of other Herpes simplex infections (in
HIV)
Adults and children (two years and above)
200-400 mg five times daily for 10-14 days.
Children below two years
Half the adult dose
TREATMENT OF VARICELLA INFECTIONS
For adults & children
20 mg/kg (up to 800 mg) four times daily for 5 days
Children below two years
200 mg four times daily for five days.
TREATMENT OF HERPES ZOSTER INFECTIONS
Adults
800 mg five times daily for seven days
Side Effects
Gastrointestinal effects, including nausea, vomiting,
diarrhoea and abdominal pain have been reported in some
patients.
Presentation
Acivir -200 DT Strip of 10 tablets
Acivir -400 DT Strip of 5 tablets
Acivir -800 DT Strip of 5 tablets |
