Composition
Novamox 125 DT
Each dispersible uncoated tablet contains ....
Amoxycillin Trihydrate IP equivalent to Amoxycillin
125 mg
Novamox 250 DT
Each dispersible uncoated tablet contains ....
Amoxycillin Trihydrate IP equivalent to Amoxycillin
250 mg
Novamox 250 Capsules
Each capsule contains ....
Amoxycillin Trihydrate IP equivalent to Amoxycillin
250 mg
Novamox 500 Capsules
Each capsule contains ....
Amoxycillin Trihydrate IP equivalent to Amoxycillin
500 mg
Novamox Dry Syrup 30 ml & 60 ml
Each 5 ml (after reconstitution) contains ....
Amoxycillin Trihydrate IP equivalent to Amoxycillin
125 mg
Novamox 125 Rediuse
Each 5 ml contains ....
Amoxycillin Trihydrate IP equivalent to Amoxycillin
125 mg
Novamox 250 Rediuse
Each 5 ml contains ....
Amoxycillin Trihydrate IP equivalent to Amoxycillin
250 mg
Novamox Paediatric Drops
Each ml (after reconstitution) contains ....
Amoxycillin Trihydrate IP equivalent to Amoxycillin
100 mg
Description
Amoxycillin is a semi synthetic
penicillin which exerts its bactericidal action by
inhibition of cell wall synthesis. It acts against
a broad spectrum of gram positive and gram negative
microorganisms.
Indications
RESPIRATORY TRACT INFECTIONS
GENITO URINARY TRACT INFECTIONS
SKIN AND SOFT TISSUE INFECTIONS
ENTERIC INFECTIONS
Bacterial diarrhoea, bacillary dysentery, shigellosis,
salmonellosis, typhoid and paratyphoid fevers and
carriers, cholecystitis and cholangitis.
DENTAL
INFECTIONS
Post oro surgical and periodontal
procedures.
Dosage
and Administration
In all infections except gonorrhoea
Adults and children 20 kgs or more
250 500 mg thrice daily at equal intervals.
Children under 20 kgs
20-40 mg/kg/day eight hourly in divided doses.
Gonorrhoea
Single dose of 3 grams.
In impaired renal function
Dosage adjustments are required
for patients with renal impairment or for patients
undergoing haemodialysis.
A dose of 250 500 mg every 16 24 hours is suggested
for adults with creatinine clearance less than 30
ml/minute.
A supplementary dose of 250 mg after every dialysis
and maintenance dose of 250 500 mg every 16 24 hours
is suggested for patients undergoing haemodialysis.
Contraindications
Hypersensitivity reactions
to penicillins.
Warnings
and Precautions
DRUG INTERACTIONS
Allopurinol: A significant
increase in skin rashes is observed when allopurinol
and ampicillin are given concurrently. A similar interaction
can occur with amoxycillin.
Bacteriostatic drugs like chloramphenicol, erythromycin
and tetracyclines may reduce the bactericidal action
of amoxycillin.
PREGNANCY
The drug can be used safely
throughout pregnancy at the normal adult doses.
NURSING MOTHERS
Amoxycillin is secreted into
breast milk in small amounts. The potential risk is
for sensitisation and skin rash in the child.
Side Effects
As with penicillins, adverse
reactions to amoxycillin are generally those related
to allergic response. These are more common in patients
with a previous history of penicillin allergy or asthma,
hay fever or urticaria. Reversible hyperactivity,
agitation, anxiety, insomnia, confusion, behavioural
changes and dizziness have been reported rare
Presentation