Duovir Tablets
Each film-coated tablet contains:
Lamivudine ………. 150 mg
Zidovudine ……….. 300 mg USP

Adults and Adolescents
The recommended oral dose of DUOVIR Tablets for adults and adolescents (at least 12 years of age) is one tablet (containing 150 mg of lamivudine and 300 mg of zidovudine) twice daily.

Dose Adjustment: Because DUOVIR Tablets are a fixed-dose combination, they should not be prescribed for patients requiring dosage adjustment such as those with reduced renal function (creatinine clearance <50 mL/min) or those experiencing dose-limiting adverse events.

A reduction in the daily dose of zidovudine may be necessary in patients with mild to moderate impaired hepatic function or liver cirrhosis. Because DUOVIR Tablets are a fixed-dose combination that cannot be adjusted for this patient population, they are not recommended for patients with impaired hepatic function.

DUOVIR Tablets are contraindicated in patients with previously demonstrated clinically significant hypersensitivity (eg, anaphylaxis, Stevens-Johnson Syndrome) to any of the components of the product.

DUOVIR Tablets...............................Blister pack of 10 tablets and Container of 60 tablets