LAMIVIR-SE 30 KIT
Each kit contains:
(A)One efavirenz tablet

Each film-coated tablet contains:
Efavirenz 600 mg

(B)Two lamivudine and stavudine fixed-dose combination tablets

Each film-coated tablet contains:
Lamivudine 150 mg and
Stavudine 30 mg

LAMIVIR-SE KIT is indicated for the treatment of HIV infection in adults.

Adult

Evening
One white LAMIVIR-S tablet (Stavudine 30 mg and lamivudine 150 mg) and one yellow tablet (efavirenz 600 mg) to be taken in the evening. It is recommended that the yellow tablet (efavirenz) be taken on an empty stomach, preferably at bedtime. Bedtime dosing improves the tolerability of nervous system side effects (see Undesirable effects ).

Dose adjustment : LAMIVIR-SE 30/ KIT should not be prescribed for patients requiring dosage adjustment, such as those with reduced renal function (creatinine clearance = 50 ml/min), or those experiencing dose-limiting adverse events.

LAMIVIR-SE 30 KIT is contraindicated in patients with clinically significant hypersensitivity to any of the components contained in the formulation.

Efavirenz
Hypersensitivity

Efavirenz is contraindicated in patients with previously demonstrated clinically significant hypersensitivity (eg, Stevens-Johnson syndrome, erythema multiforme, or toxic skin eruptions) to any of the components of this product.

Contraindicated Drugs

For some drugs, competition for CYP3A by efavirenz could result in inhibition of their metabolism and create the potential for serious and/or life-threatening adverse reactions (eg, cardiac arrhythmias, prolonged sedation, or respiratory depression). Drugs that are contraindicated with efavirenz are listed in Table 3.

Table 3: Drugs That Are Contraindicated or Not Recommended for Use with Efavirenz

LAMIVIR-SE KIT…………………………. Carton of 10 kits